Source: Vulvovaginal Dermatology 2010
Atopic dermatitis. Red, edematous, excoriated plaques of eczematous dermatitis are characteristic of localized atopic dermatitis and contact dermatitis.
Psoriasis. Well demarcated, thickened, scaling, red plaques are classic for psoriasis and correlate with the microscopic picture of acanthosis.
Lichen sclerosus. A well-demarcated, hypopigmented, crinkled plaque is typical for lichen sclerosus.
Lichen planus. Vestibular erosion is the most common presentation of vulvar lichen planus; the surrounding, irregular, and coalescing white linear papules are less common but classic and pathognomonic.
Bullous and cicatricial pemphigoid. Mucous membrane erosions with surrounding white epithelium and loss of vulvar architecture is typical but nonspecific for cicatricial pemphigoid, as well as for lichen planus and pemphigus vulgaris
Crohn disease. Edema of the vulva and skin tags are typical findings in anogenital Crohn disease
Plasma cell vulvitis (Zoon’s vulvitis). Vulvitis plasmacellularis has a very characteristic feature of wel-demarcated dark redness or brown-red patches, most often in the vestibule.