Rx – All “B”

Dec 6, 2019 admin DƯỢC KHOA 0

BACTERIAL ENDOCARDITIS: PROPHYLAXIS

Comment: Bacterial endocarditis prophylaxis is appropriate for persons with a history of previous infective endocarditis, persons with a prosthetic cardiac valve or prosthetic material used for valve repair, cardiac transplant patients who develop cardiac valvulopathy, congenital heart disease (CHD), unrepaired cyanotic CHD including palliative shunts and conduits, completely repaired congenital heart defect(s) with prosthetic material or device, whether placed by surgery or by catheter intervention, during the first 6 months after the procedure, repaired CHD with residual defects at the site or adjacent to the site of a prosthetic patch or prosthetic device (which may inhibit endothelialization), or any other condition deemed to place a patient at high risk.

DENTAL, ORAL, RESPIRATORY TRACT, OR ESOPHAGEAL PROCEDURES

  • amoxicillin (B)(G) 2 g PO 30-60 minutes before procedure as a single dose or 3 g 1 hour before procedure and 1.5 g 6 hours later
    Pediatric: 50 mg/kg as a single dose or 50 mg/kg (max 3 g) 1 hour before procedure and (max 1.5 g) 25 mg/kg 6 hours later; =40 kg: same as adult; see pages 554-557 for dose by weight
    Amoxil Cap: 250, 500 mg; Tab: 875*mg; Chew tab: 125, 200, 250, 400 mg (cherry-banana-peppermint) (phenylalanine); Oral susp: 125, 250 mg/5 ml (80, 100, 150 ml) (strawberry); 200, 400 mg/5 ml (50, 75, 100 ml) (bubble gum); Oral drops: 50 mg/ml (30 ml) (bubble gum)
    Trimox Tab: 125, 250 mg; Cap: 250, 500 mg; Oral susp: 125, 250 mg/5 ml (80, 100, 150 ml) (raspberry-strawberry)
  • ampicillin (B)(G) 2 g PO/IM/IV 30-60 minutes before procedure
    Pediatric: 50 mg/kg PO/IM/IV 30-60 minutes before procedure

Omnipen, Principen Cap: 250, 500 mg; Oral susp: 125, 250 mg/5 ml (100, 150, 200 ml) (fruit)
Unisyn Vial: 1.5, 3 g

  • azithromycin (B) 500 mg 30-60 minutes before procedure
    Pediatric: 15 mg/kg 30-60 minutes before procedure; max 500 mg; see page 559 for dose by weight
    Zithromax Tab: 250, 500, 600 mg; Oral susp: 100 mg/5 ml (15 ml); 200 mg/5 ml (15, 22.5, 30 ml) (cherry)
  • cefazolin (B) 1 g IM/IV 30-60 minutes before procedure
    Pediatric: 25 mg/kg IM/IV 30-60 minutes before procedure
    Ancef Vial: 250, 500 mg; 1, 5 g
    Kefzol Vial: 500 mg; 1 g
  • ceftriaxone (B)(G) 1 g IM/IV as a single dose
    Pediatric: 50 mg/kg IM/IV as a single dose
    Rocephin Vial: 250, 500 mg; 1, 2 g
  • cephalexin (B)(G) 2 g as a single dose 30-60 minutes before procedure
    Pediatric: 50 mg/kg as a single dose 30-60 minutes before procedure; see page 568
    for dose by weight
    Keflex Cap: 250, 333, 500, 750 mg; Oral susp: 125, 250 mg/5 ml (100, 200 ml) (strawberry)
  • clarithromycin (C)(G) 500 mg or 500 mg ext-rel as a single dose 30-60 minutes before procedure
    Pediatric: 15 mg/kg as a single dose 30-60 minutes before procedure; see page 569 for dose by weight
    Biaxin Tab: 250, 500 mg
    Biaxin Oral Suspension Oral susp: 125, 250 mg/5 ml (50, 100 ml) (fruitpunch)
    Biaxin XL Tab: 500 mg ext-rel

clindamycin (B)(G) 600 mg PO as a one time single dose or 300 mg 30-60 minutes before procedure and 150 mg 6 hours later; take with a full glass of water Pediatric: 20 mg/kg (max 300 mg) 1 hour before procedure and 10 mg/kg (max 150 mg) 6 hours later; take with a full glass of water; see page 570 for dose by weight
Cleocin (G) Cap: 75 (tartrazine), 150 (tartrazine), 300 mg; Vial: 150 mg/ml (2, 4 ml) (benzyl alcohol)
Cleocin Pediatric Granules (G) Oral susp: 75 mg/ml (100 ml)(cherry)

erythromycin estolate (B)(G) 1 g 1 hour before procedure; then 500 mg 6 hours later
Pediatric: 20 mg/kg 1 hour before procedure; then 10 mg/kg 6 hours later; see page 573 for dose by weight
Ilosone Pulvule: 250 mg; Tab: 500 mg; Liq: 125, 250 mg/5 ml (100 ml)
Comment: erythromycin may increase INR with concomitant warfarin, as well as increase serum level of digoxin, benzodiazepines and statins.

penicillin V potassium (B)(G) 2 g 1 hour before procedure; then 1 g 6 hours later or 2 g 1 hour before procedure; then 1 g q 6 hours x 8 doses
Pediatric: <60 lb: 1 g 1 hour before procedure; then 500 mg 6 hours later or 1 g 1 hour before procedure; then 500 mg q 6 hours x 8 doses; >12 years: same as adult; see page 583 for dose by weight
Pen-Vee K Tab: 250, 500 mg; Oral soln: 125 mg/5 ml (100, 200 ml); 250 mg/5 ml (100, 150, 200 ml)

BACTERIAL VAGINOSIS (BV; GARDNERELLA VAGINALIS)

PROPHYLAXIS AND RESTORATION OF VAGINAL ACIDITY

  • acetic acid/oxyquinolone (C) one full applicator intravaginally bid for up to 30 days
    Pediatric: not recommended
    Relagard Gel: acet acid 0.9%/oxyq 0.025% (50 g tube w. applicator)
    Comment: The following treatment regimens for bacterial vaginosis are published in the 2015 CDC Sexually Transmitted Diseases Treatment Guidelines. Treatment regimens are presented by generic drug name first, followed by information about brands and dose forms. BV is associated with adverse pregnancy outcomes, including premature rupture of the membranes, preterm labor, preterm birth, intraamniotic infection, and postpartum endometritis. Therefore, treatment is recommended for all pregnant women with symptoms or positive screen.

RECOMMENDED REGIMENS

Regimen 1
metronidazole 500 mg bid x 7 days
Regimen 2
metronidazole gel 0.75% one full applicatorful (5 g) once daily x 5 days
Regimen 3
clindamycin cream 2% one full applicatorful (5 g) intravaginally once daily at bedtime x 5 days

CDC Alternate Regimens

Regimen 1. tinidazole 2 g once daily x 2 days
Regimen 2. tinidazole 1 g once daily x 5 days
Regimen 3. clindamycin 300 mg bid x 7 days
Regimen 4. clindamycin ovules 100 mg intravaginally once daily at bedtime x 3 days

  • Drug Brands and Dose Forms
    clindamycin (B)
    Cleocin (G) Cap: 75 (tartrazine), 150 (tartrazine), 300 mg
    Cleocin Pediatric Granules (G) Oral susp: 75 mg/5 ml (100 ml) (cherry)
    Cleocin Vaginal Cream Vag crm: 2% (21, 40 g tubes w. applicator)
    Cleocin Vaginal Ovules Vag supp: 100 mg
  • metronidazole (not for use in 1st; B in 2nd, 3rd)
    Flagyl Tab: 250*, 500*mg
    Flagyl 375 Cap: 375 mg
    Flagyl ER Tab: 750 mg ext-rel
    MetroGel-Vaginal, Vandazole Vag gel: 0.75% (70 g w. applicator) (parabens)

Comment: Alcohol is contraindicated during treatment with oral metronidazole and for 72 hours after therapy due to a possible disulfiram-like reaction (nausea, vomiting, flushing, headache).

  • tinidazole (not for use in 1st; B in 2nd, 3rd)
    Tindamax Tab: 250*, 500*mg
    Comment: Alcohol is contraindicated during treatment with oral tinidazole and for 72 hours after therapy due to a possible disulfiram-like reaction (nausea, vomiting, flushing, headache).

BALDNESS: MALE PATTERN

TYPE II 5-ALPHA-REDUCTASE SPECIFIC INHIBITOR

  • finasteride (X)(G) 1 mg daily
    Propecia Tab: 1 mg
    Comment: Pregnant women should not touch broken finasteride tabs. Use of
    Propecia, a 5-alpha reductase inhibitor, is associated with low but increased risk of high-grade prostate cancer.

PERIPHERAL VASODILATOR

  • minoxidil topical soln (C) 1 ml from dropper or 6 sprays bid
    Pediatric: <18 years: not recommended
    Rogaine for Men (OTC) Regular soln: 2% (60 ml w. applicator) (alcohol 60%);
    Extra strength soln: 5% (60 ml w. applicator) (alcohol 30%)
    Rogaine for Women (OTC) Regular soln: 2% (60 ml w. applicator) (alcohol 60%)
    Comment: Do not use minoxidil on abraded or inflamed scalp.

BELL’S PALSY

  • prednisone (C)(G) 80 mg once daily x 3 days; then 60 mg daily x 3 days; then 40 mg daily x 3 days; then 20 mg x 1 dose; then discontinue
    Deltasone Tab: 2.5*, 5*, 10*, 20*, 50*mg

BENIGN ESSENTIAL TREMOR ANTI-PARKINSON’S AGENT

  • amantadine (C)(G) 200 mg daily or 100 mg bid; 4 tsp of syrup once daily or 2 tsp bid
    Symmetrel Tab: 100 mg; Syr: 50 mg/5 ml (raspberry)

BETA-BLOCKER

  • propranolol (C)(G)
    Inderal initially 40 mg bid; usual range 160-240 mg/day
    Tab: 10*, 20*, 40*, 60*, 80*mg
    Inderal LA initially 80 mg once daily in a single dose; increase q 3-7 days; usual range 120-160 mg/day; max 320 mg/day in a single dose
    Cap: 60, 80, 120, 160 mg sust-rel
    InnoPran XL initially 80 mg q HS; max 120 mg/day
    Cap: 80, 120 mg ext-rel

BENIGN PROSTATIC HYPERPLASIA (BPH)

ALPHA-1 BLOCKERS
Comment: Educate patient regarding potential side effect of hypotension especially
with first dose. Usually start at lowest dose and titrate upward.

  • doxazosin (C)
    Cardura initially 1 mg daily; may double dose every 1-2 weeks; max 8 mg/day
    Tab: 1*, 2*, 4*, 8*mg
    Cardura XL initially 4 mg once daily with breakfast; may titrate after 3-4 weeks; max 8 mg/day
    Tab: 4, 8 mg ext-rel
  • silodosin (B) 8 mg once daily; CrCl 30-50 mL/min: 4 mg once daily
    Rapaflo Cap: 4, 8 mg
  • terazosin (C)(G) initially 1 mg q HS; titrate up to 10 mg once daily; max 20 mg/day
    Hytrin Cap: 1, 2, 5, 10 mg

ALPHA-1A BLOCKERS

  • alfuzosin (B)(G) 10 mg once daily taken immediately after the same meal each day
    UroXatral Tab: 10 mg ext-rel
  • tamsulosin (B)(G) initially 0.4 mg once daily; may increase to 0.8 mg daily after 2-4 weeks if needed
    Flomax Cap: 0.4 mg
    Comment: May take Flomax 0.4 mg plus imitrex 0.5 mg once daily as combination therapy.

TYPE II 5-ALPHA-REDUCTASE INHIBITOR
Comment: Pregnant women and women of childbearing age should not handle finasteride. Monitor for potential side effects of decreased libido and/or impotence.
Low, but increased risk of being diagnosed with high-grade prostate cancer.

  • finasteride (X) 5 mg once daily
    Proscar Tab: 5 mg

TYPES I AND II 5-ALPHA-REDUCTASE INHIBITOR
Comment: Pregnant women and women of childbearing age should not handle dutasteride. Monitor for potential side effects of decreased libido and/or impotence.
Low, but increased risk of being diagnosed with high-grade prostate cancer.

  • dutasteride (X)(G) 0.5 mg once daily
    Avodart Cap: 0.5 mg
    Comment: May take Avodart 0.5 mg with Flomax 0.4 mg once daily as combination therapy.

TYPE I AND II 5-ALPHA-REDUCTASE INHIBITOR/ALPHA-1A BLOCKER

  • dutasteride/tamsulosin (X)(G) take 1 cap once daily after the same meal each day
    Jalyn Cap: duta 0.5 mg/tam 0.4 mg

PHOSPHODIESTERASE TYPE 5 (PDE5) INHIBITORS, CGMP-SPECIFIC
Comment: Oral PDE5 inhibitors are contraindicated in patients taking nitrates.
Caution with history of recent MI, stroke, life-threatening arrhythmia, hypotension, hypertension, cardiac failure, unstable angina, retinitis pigmentosa, CYP3A4 inhibitors
(e.g., cimetidine, the azoles, erythromycin, grapefruit juice), protease inhibitors (e.g., ritonavir), CYP3A4 inducers (e.g., rifampin, carbamaepine, phenytoin,  phenobarbital), alcohol, antihypertensive agents. Side effects include headache, flushing, nasal congestion, rhinitis, dyspepsia, and diarrhea.

  • tadalafil (B) 5 mg once daily at the same time each day; CrCl 30-50 mL/min: initially 2.5 mg; CrCl <30 mL/min: not recommended; Concomitant alpha blockers: not recommended
    Cialis Tab: 2.5, 5, 10, 20 mg

BILE ACID DEFICIENCY

BILE ACID

  • ursodiol (B)
    Dissolution of radiolucent non-calcified gallstones <20 mm diameter: 8-10 mg/kg/day in 2-3 divided doses; Prevention: 13-15 mg/kg/day in 4 divided doses
    Pediatric: not recommended
    Actigall Cap: 300 mg
    Comment: ursodiol decreases the amount of cholesterol produced by the liver and absorbed by the intestines. It helps break down cholesterol that has formed into stones in the gallbladder. ursodiol increases bile flow in patients with primary biliary cirrhosis. It is used to treat small gallstones in people who cannot have cholecystectomy surgery and to prevent gallstones in overweight patients undergoing rapid weight loss. ursodiol is not for treating gallstones that are calcified.

BINGE EATING DISORDER

CENTRAL NERVOUS SYSTEM (CNS) STIMULANT

  • lisdexamfetamine dimesylate (C)(II) swallow whole or may open and mix/dissolve contents of cap in yogurt, water, orange juice and take immediately; 30 mg once daily in the AM; may adjust in increments of 20 mg at weekly intervals; target dose 50-70 mg/day; max 70 mg/day; GFR 15-<30 mL/min: max 50 mg/day; GFR <15 mL/min, ESRD: max 30 mg/day
    Vyvanse Cap: 10, 20, 30, 40, 50, 60 70 mg
    Comment: Vyvanse is not approved or recommended for weight loss treatment of obesity.

BIPOLAR I DISORDER: DEPRESSION
Comment: The cornerstone of treatment for Bipolar I Disorder: Depression is mood-stabilizers (lithium and valproate). Common adjunctive agents include antiepileptics, antipsychotics, and combination agents. Mounting evidence suggests that antidepressants aren’t effective in the treatment of  bipolar depression. A major study funded by the National Institute of Mental Health (NIMH) showed that adding an antidepressant to a mood stabilizer was no more effective in treating bipolar I depression than using a mood stabilizer alone. Another NIMH study found that antidepressants work no better than placebo. If antidepressants are used at all, they should be combined with a mood stabilizer such as lithium or valproic acid. Taking an antidepressant without a mood stabilizer is likely to trigger a manic episode. Antidepressants can increase mood cycling. Many experts believe that over time, antidepressant use in people with bipolar disorder has a mood destabilizing effect, increasing the frequency of manic and depressive episodes. Drugs and conditions that can mimic bipolar I disorder include thyroid disorders, corticosteroids, antidepressants, adrenal disorders (e.g. Addison’s disease, Cushing’s syndrome), antianxiety drugs, drugs for Parkinson’s disease, vitamin B12 deficiency, neurological disorders (e.g. epilepsy, multiple sclerosis).

MOOD STABILIZERS

Lithium Salts Mood Stabilizer

  • lithium carbonate (D)(G) swallow whole; Usual maintenance: 900-1200 mg/day in 2-3 divided doses
    Pediatric: not recommended
    Lithobid Tab: 300 mg slow-rel
    Comment: Signs and symptoms of lithium toxicity can occur below 2 mEq/L and include blurred vision, tinnitus, weakness, dizziness, nausea, abdominal pains, vomiting, diarrhea to (severe) hand tremors, ataxia, muscle twitches, nystagmus, seizures, slurred speech, decreased level of consciousness, coma, death.

Valproate Mood Stabilizer

  • divalproex sodium (D)(G) take once daily; swallow ext-rel form whole; initially 25 mg/kg/day in divided doses; max 60 mg/kg/day; Elderly: reduce initial dose and titrate slowly
    Pediatric: not recommended
    Depakene Cap: 250 mg; Syr: 250 mg/5 ml (16 oz)
    Depakote Tab: 125, 250 mg
    Depakote ER Tab: 250, 500 mg ext-rel
    Depakote Sprinkle Cap: 125 mg

ANTIEPILEPTICS

  • carbamazepine (D) ext-rel oral forms should be swallowed whole; may open caps and sprinkle on applesauce (do not crush or chew beads); initially 400 mg/day in 2 divided doses; adjust in increments of 200 mg/day; max 1.6 g/day. Elderly: reduce initial dose and titrate slowly; oral doses are preferred; IV administration is recommended when the patient is unable to swallow an oral form (see Carnexiv)
    Pediatric: not recommended
    Carbatrol (G) Cap: 200, 300 mg ext-rel
    Carnexiv Vial: 10 mg/ml (20 ml)
    Comment: The total daily dose of Carnexiv is 70% of the total daily oral carbamazepine dose (see mfr pkg insert for dosage conversion table). The total daily dose should be equally divided into four 30-minute infusions, separated by 6 hours. Must be diluted prior to administration. Patients should be switched back to oral carbamazepine at their previous total daily oral dose and frequency of administration as soon as clinically appropriate. The use of Carnexiv for more than 7 consecutive days has not been studied.
    Equetro (G) Cap: 100, 200, 300 mg ext-rel
    Tegretol (G) Tab: 200*mg; Chew tab: 100*mg; Oral susp: 100 mg/5 ml (450 ml; citrus-vanilla)
    Tegretol XR (G) Tab: 100, 200, 400 mg ext-rel
    Comment: carbamazepine is indicated in mixed episodes in bipolar I disorder.
  • lamotrigine (C)(G) Not taking an enzyme-inducing antiepileptic drug (EIAED) (e.g., phenytoin, carbamazepine, phenobarbital, primidone, valproic acid): 25 mg once daily x 2 weeks; then 50 mg once daily x 2 weeks; then 100 mg once daily x 2 weeks; then target dose 200 mg once daily; Concomitant valproic acid: 25 mg every other day x 2 weeks; then 25 mg once daily x 2 weeks; then 50 mg once daily x 1 week; then target dose 100 mg once daily; Concomitant EIAED, not valproic acid: 50 mg once daily x 2 weeks; then 100 mg daily in divided doses; then increase weekly by 100 mg in divided doses to target dose 400 mg/day in divided doses daily
    Pediatric: not recommended
    Lamictal Tab: 25*, 100*, 150*, 200*mg
    Lamictal Chewable Dispersible Tab Chew tab: 2, 5, 25, 50 mg (black current)
    Lamictal ODT ODT: 25, 50, 100, 200 mg
    Lamictal XR Tab: 25, 50, 100, 200 mg ext-rel
    Comment: lamotrigine is indicated for maintenance treatment of bipolar I disorder.
    See mfr pkg insert for drug interactions, interactions with contraceptives and hormone replacement therapy, and discontinuation protocol

ANTIPSYCHOTICS
Comment: Side effects of antipsychotics include drowsiness, weight gain, sexual dysfunction, dry mouth, constipation, blurred vision.

  • aripiprazole (C)(G) initially 15 mg once daily; may increase to max 30 mg/day
    Pediatric: <10 years: not recommended; =10-17 years: initially 2 mg/day in a single dose for 2 days; then increase to 5 mg/day in a single dose for 2 days; then increase to target dose of 10 mg/day in a single dose; may increase by 5 mg/day at weekly intervals as needed to max 30 mg/day
    Abilify Tab: 2, 5, 10, 15, 20, 30 mg
    Abilify Discmelt Tab: 15 mg orally-disint (vanilla) (phenylalanine)
    Abilify Maintena Vial: 300, 400 mg ext-rel pwdr for IM injection after reconstitution; 300, 400 mg single-dose prefilled dual-chamber syringes w. supplies
    Comment: Abilify is indicated for acute and maintenance treatment of mixed episodes in bipolar I disorder, as monotherapy or as adjunct to lithium or valproic acid.
  • asenapine (C) allow SL tab to dissolve on tongue; do not split, crush, chew, or swallow; do not eat or drink for 10 minutes after administration; Monotherapy: 10 mg bid; Adjunctive therapy: 5 mg bid; may increase to max 10 mg bid
    Pediatric: <10 years: not established; 10-17 years: Monotherapy: initially 2.5 mg bid; may increase to 5 mg bid after 3 days; then to 10 mg bid after 3 more days; max 10 mg bid
    Saphris SL tab: 2, 5, 5, 10 mg (black cherry)
    Comment: Saphris is indicated for acute treatment of manic or mixed episodes in bipolar I disorder, as monotherapy or as adjunct to lithium or valproic acid.
  • cariprazine (NE)
    Pediatric: not established
    Vraylar Cap: 1.5, 3, 4.5, 6 mg; 7-count (1 x 1.5 mg, 6 x 3 mg) mixed blister pck
    Comment: Vraylar is an atypical antipsychotic with partial agonist activity at D2 and 5-HT1A receptors and antagonist activity at 5-HT2A receptors. It is indicated for acute treatment of mixed episodes in bipolar I disorder. There is a Vraylar pregnancy exposure registry that monitors pregnancy outcomes in women exposed to Vraylar during pregnancy. For more information, contact the National Pregnancy Registry for Atypical Antipsychotics at 1-866-961-2388 or visit https://womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry.
    Safety and effectiveness in pediatric patients have not been established.
  • lurasidone (B) initially 20 mg once daily; usual range 20 to max 120 mg/day; take with food; CrCl <50 mL/min, moderate hepatic impairment (Child Pugh 7-9): max 80 mg/day; Child Pugh 10-15): max 40 mg/day
    Pediatric: not established
    Latuda Tab: 20, 40, 60, 80, 120 mg
    Comment: Latuda is indicated for major depressive episodes associated with bipolar I disorder as monotherapy and as adjunctive therapy with lithium or valproic acid. Contraindicated with concomitant strong CYP3A4 inhibitors (e.g., ketoconazole, voriconazole, clarithromycin, ritonavir) and inducers (e.g., phenytoin, carbamazepine, rifampin, St. John’s wort); see mfr pkg insert if patient taking moderate CYP3A4 inhibitors (e.g., diltiazem, atazanavir, erythromycin, fluconazole, verapamil)
  • quetiapine fumarate (C)
    SeroQUEL initially 25 mg bid, titrate q 2nd or 3rd day in increments of 25-50 mg bid-tid; usual maintenance 400-600 mg/day in 2-3 divided doses
    Pediatric: <10 years: not recommended; =10-17 years: initially 25 mg bid, titrate q 2nd or 3rd day in increments of 25-50 mg bid-tid; max 600 mg/day in 2-3 divided doses
    Tab: 25, 50, 100, 200, 300, 400 mg
    SeroQUEL XR swallow whole; administer once daily in the PM; Day 1: 50 mg;
    Day 2: 100 mg; Day 3: 200 mg; Day 4: 300 mg; usual range 400-600 mg/day
    Pediatric: <18 years: not recommended
    Tab: 50, 150, 200, 300, 400 mg ext-rel
  • risperidone (C) Tab: initially 2-3 mg once daily; may adjust at 24 hour intervals by 1 mg/day; usual range 1-6 mg/day; max 6 mg/day; Oral soln: do not take with cola or tea; M-tab: dissolve on tongue with or without fluid; Consta: administer deep IM in the deltoid or gluteal; give with oral respirodone or other antipsychotic x 3 weeks; then stop oral form; 25 mg IM every 2 weeks; max 50 mg every 2 weeks
    Risperdal
    Pediatric: <5 years: not established; 5-10 years: initially 0.5 mg once daily at the same time each day adjust at 24 hour intervals by 0.5-1 mg to target dose 1-2.5 mg/day; usual range 1-6 mg/day; max 6 mg/day; >10 years: same as adult
    Tab: 0.25, 0.5, 1, 2, 3, 4 mg; Oral soln: 1 mg/ml (100 ml)
    Risperdal Consta
    Pediatric: <18 years: not established
    Vial: 12.5, 25, 37.5, 50 mg pwdr for long-acting IM inj after reconstitution, single-use, w. diluent and supplies
    Risperdal M-Tab
    Pediatric: <10 years: not established; =10 years: same as adult
    Tab: 0.5, 1, 2, 3, 4 mg orally-disint (phenylalanine)
    Comment: Risperdol tabs, oral solution, and M-tabs are indicated for the shortterm monotherapy of acute mania or mixed episodes associated with bipolar I disorder, or in combination with lithium or valproic acid in adults
    Risperdol Consta is indicated as monotherapy or adjunctive therapy to lithium or valproic acid for the maintenance treatment mania and mixed episodes in
    bipolar I disorder.
  • ziprasidone (C)(G) Adult: take with food; initially 40 mg bid; on day 2, may increase to 60-80 mg bid; Elderly: lower initial dose and titrate slowly
    Pediatric: not recommended
    Geodon Cap: 20, 40, 60, 80 mg
    Comment: Geodon is indicated for acute and maintenance treatment of mixed episodes in bipolar I disorder, as monotherapy or as adjunct to lithium or
    valproic acid.

COMBINATION AGENTS
Thienobenzodiazepine/Selective Serotonin Reuptake Inhibitor Combinations

  • fluoxetine (C)(G)
    Prozac initially olanzapine 5 mg plus fluoxetine 20 mg daily in the PM; range olanzapine 5-12.5 mg plus fluoxetine 20-50 mg; risk of hypotension, or hepatic impairment, slow metabolizers, or sensitive to olanzapine, initially olanzapine 2.5-5 mg plus fluoxetine 20 mg daily in the PM; fluoxetine doses >20 mg/day may be divided into AM and noon doses
    Pediatric: not recommended
    Cap: 10, 20, 40 mg; Tab: 30*, 60*mg; Oral soln: 20 mg/5 ml (4 oz) (mint)
    Prozac Weekly following daily fluoxetine therapy at 20 mg/day for 13 weeks, may initiate
    Prozac Weekly 7 days after the last 20 mg fluoxetine dose
    Pediatric: not recommended
  • olanzapine/fluoxetine (C) initially 1 x 6/25 cap once daily in the PM; titrate; max 1 x 12/50 cap once daily in the PM
    Pediatric: <10 years: not recommended; 10-17 years: initially 1 x 3/25 cap once daily in the PM; max 1 x 12/50 cap once daily in the PM
    Symbyax
    Cap: Symbyax 3/25: olan 3 mg/fluo 25 mg
    Symbyax 6/25: olan 6 mg/fluo 25 mg
    Symbyax 6/50: olan 6 mg/fluo 50 mg
    Symbyax 12/25: olan 12 mg/fluo 25 mg
    Symbyax 12/50: olan 12 mg/fluo 50 mg
    Comment: Symbyax is indicated for the treatment of depressive episodes associated with bipolar I disorder and treatment-resistant depression (TRD).

BIPOLAR I DISORDER: MANIA
Comment: The cornerstone of treatment for Bipolar I Disorder: Mania is mood stabilizers
(lithium and valproic acid). Common adjunctive agents include antiepileptics
and antipsychotics. Drugs and conditions that can mimic bipolar I disorder include
thyroid disorders, corticosteroids, antidepressants, adrenal disorders (e.g., Addison’s
disease, Cushing’s syndrome), antianxiety drugs, drugs for Parkinson’s disease, vitamin
B12 deficiency, neurological disorders (e.g., epilepsy, multiple sclerosis).

MOOD STABILIZERS
Lithium Salts Mood Stabilizer

lithium carbonate (D)(G) swallow whole; Usual maintenance: 900-1200 mg/day in
2-3 divided doses
Pediatric: not recommended
Lithobid Tab: 300 mg slow-rel
Comment: Signs and symptoms of lithium toxicity can occur below 2 mEq/L and
include blurred vision, tinnitus, weakness, dizziness, nausea, abdominal pains,
vomiting, diarrhea to (severe) hand tremors, ataxia, muscle twitches, nystagmus,
seizures, slurred speech, decreased level of consciousness, coma, death.
Valproate Mood Stabilizer

divalproex sodium (D)(G) take once daily; swallow ext-rel form whole; initially 25
mg/kg/day in divided doses; max 60 mg/kg/day; Elderly: reduce initial dose and titrate
slowly
Pediatric: not recommended
Depakene Cap: 250 mg; Syr: 250 mg/5 ml (16 oz)
Depakote Tab: 125, 250 mg
Depakote ER Tab: 250, 500 mg ext-rel
Depakote Sprinkle Cap: 125 mg
ANTIEPILEPTICS
carbamazepine (D) ext-rel forms should be swallowed whole; may open caps and
sprinkle on applesauce (do not crush or chew beads); initially 400 mg/day in 2 divided
doses; adjust in increments of 200 mg/day; max 1.6 g/day. Elderly: reduce initial
dose and titrate slowly; oral doses are preferred; IV administration is recommended
when the patient is unable to swallow an oral form (see Carnexiv)
Pediatric: not recommended
Carbatrol (G) Cap: 200, 300 mg ext-rel
Carnexiv Vial: 10 mg/ml (20 ml)
Comment: The total daily dose of Carnexiv is 70% of the total daily oral
carbamazepine dose (see mfr pkg insert for dosage conversion table). The total
daily dose should be equally divided into four 30-minute infusions, separated
by 6 hours. Must be diluted prior to administration. Patients should be switched
back to oral carbamazepine at their previous total daily oral dose and frequency
of administration as soon as clinically appropriate. The use of Carnexiv for
more than 7 consecutive days has not been studied.
Equetro (G) Cap: 100, 200, 300 mg ext-rel
Tegretol (G) Tab: 200*mg; Chew tab: 100*mg; Oral susp: 100 mg/5 ml (450 ml;
citrus-vanilla)
Tegretol XR (G) Tab: 100, 200, 400 mg ext-rel
Comment: carbamazepine is indicated in mixed episodes in bipolar I disorder.
lamotrigine (C)(G) Not taking an enzyme-inducing antiepileptic drug (EIAED) (e.g.,
phenytoin, carbamazepine, phenobarbital, primidone, valproic acid): 25 mg once
daily x 2 weeks; then 50 mg once daily x 2 weeks; then 100 mg once daily x 2 weeks;
then target dose 200 mg once daily; Concomitant valproic acid: 25 mg every other
day x 2 weeks; then 25 mg once daily x 2 weeks; then 50 mg once daily x 1 week; then
target dose 100 mg once daily; Concomitant EIAED, not valproic acid: 50 mg once
daily x 2 weeks; then 100 mg daily in divided doses; then increase weekly by 100 mg
in divided doses to target dose 400 mg/day in divided doses daily
Pediatric: not recommended
Lamictal Tab: 25*, 100*, 150*, 200*mg
Lamictal Chewable Dispersible Tab Chew tab: 2, 5, 25, 50 mg (black current)
Lamictal ODT ODT: 25, 50, 100, 200 mg
Lamictal XR Tab: 25, 50, 100, 200 mg ext-rel
Comment: lamotrigine is indicated for maintenance treatment of bipolar I disorder.
See mfr pkg insert for drug interactions, interactions with contraceptives and
hormone replacement therapy, and discontinuation protocol
topiramate (D)(G) initially 25 mg daily in the PM; then 25 mg bid; then, 25 mg in the
AM and 50 mg in the PM; then, 50 mg bid
Pediatric: <12 years: not recommended
Topamax Tab: 25, 50, 100, 200 mg
Topamax Sprinkle Caps Cap: 15, 25 mg
ANTIPSYCHOTICS
Comment: Side effects of antipsychotics include drowsiness, weight gain, sexual
dysfunction, dry mouth, constipation, blurred vision.
aripiprazole (C)(G) initially 15 mg once daily; may increase to max 30 mg/day
Pediatric: <10 years: not recommended; =10-17 years: initially 2 mg/day in a single
dose for 2 days; then increase to 5 mg/day in a single dose for 2 days; then increase
to target dose of 10 mg/day in a single dose; may increase by 5 mg/day at weekly
intervals as needed to max 30 mg/day
Abilify Tab: 2, 5, 10, 15, 20, 30 mg
Abilify Discmelt Tab: 15 mg orally-disint (vanilla) (phenylalanine)
Abilify Maintena Vial: 300, 400 mg ext-rel pwdr for IM injection after reconstitution;
300, 400 mg single-dose prefilled dual-chamber syringes w. supplies
Comment: Abilify is indicated for acute and maintenance treatment of mixed
episodes in bipolar I disorder, as monotherapy or as adjunct to lithium or
valproic acid.
asenapine (C) allow SL tab to dissolve on tongue; do not split, crush, chew, or swallow;
do not eat or drink for 10 minutes after administration; Monotherapy: 10 mg bid;
Adjunctive therapy: 5 mg bid; may increase to max 10 mg bid
Pediatric: <10 years: not established; 10-17 years: Monotherapy: initially 2.5 mg bid;
may increase to 5 mg bid after 3 days; then to 10 mg bid after 3 more days; max 10
mg bid
Saphris SL tab: 2, 5, 5, 10 mg (black cherry)
Comment: Saphris is indicated for acute treatment of manic or mixed episodes
in bipolar I disorder, as monotherapy or as adjunct to lithium or valproic acid. y
cariprazine (NE)
Pediatric: not established
Vraylar Cap: 1.5, 3, 4.5, 6 mg; 7-count (1 x 1.5 mg, 6 x 3 mg) mixed blister pck
Comment: Vraylar is an atypical antipsychotic with partial agonist activity at D2
and 5-HT1A receptors and antagonist activity at 5-HT2A receptors. It is indicated
for acute treatment of mixed episodes in bipolar I disorder. There is a Vraylar
pregnancy exposure registry that monitors pregnancy outcomes in women
exposed to Vraylar during pregnancy. For more information, contact the National
Pregnancy Registry for Atypical Antipsychotics at 1-866-961-2388 or visit https://
womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry.
Safety and effectiveness in pediatric patients have not been established.
chlorpromazine (C)(G) initially 10 mg tid-qid; may increase semi-weekly by 25-50
mg/day
Pediatric: =6 months: initially 0.25 mg/lb every 4-6 hours prn or 0.5 mg/lb rectally
q 6-8 hours prn
Th orazine Tab: 10, 25, 50, 100, 200 mg; Spansule: 30, 75, 150 mg sust-rel; Syr:
10 mg/5 ml (4 oz) (orange custard); Oral conc: 30 mg/ml (4 oz); 100 mg/ml (2, 8
oz); Supp: 25, 100 mg
Comment: chlorpromazine is indicated for rapid control of severe psychotic
symptoms.
lurasidone (B) initially 20 mg once daily; usual range 20 to max 120 mg/day; take
with food; CrCl <50 mL/min, moderate hepatic impairment (Child Pugh 7-9): max 80
mg/day; Child Pugh 10-15): max 40 mg/day
Pediatric: not established
Latuda Tab: 20, 40, 60, 80, 120 mg
Comment: Latuda is indicated for major depressive episodes associated with
bipolar I disorder as monotherapy and as adjunctive therapy with lithium or
valproic acid. Contraindicated with concomitant strong CYP3A4 inhibitors
(e.g., ketoconazole, voriconazole, clarithromycin, ritonavir) and inducers
(e.g., phenytoin, carbamazepine, rifampin, St. John’s wort); see mfr pkg insert
if patient taking moderate CYP3A4 inhibitors (e.g., diltiazem, atazanavir,
erythromycin, fluconazole, verapamil)
quetiapine fumarate (C)
SeroQUEL initially 25 mg bid, titrate q 2nd or 3rd day in increments of 25-50
mg bid-tid; usual maintenance 400-600 mg/day in 2-3 divided doses
Pediatric: <10 years: not recommended; =10-17 years: initially 25 mg bid, titrate
q 2nd or 3rd day in increments of 25-50 mg bid-tid; max 600 mg/day in 2-3
divided doses
Tab: 25, 50, 100, 200, 300, 400 mg
SeroQUEL XR swallow whole; administer once daily in the PM; Day 1: 50 mg;
Day 2: 100 mg; Day 3: 200 mg; Day 4: 300 mg; usual range 400-600 mg/day
Pediatric: <18 years: not recommended
Tab: 50, 150, 200, 300, 400 mg ext-rel
risperidone (C) Tab: initially 2-3 mg once daily; may adjust at 24 hour intervals
by 1 mg/day; usual range 1-6 mg/day; max 6 mg/day; Oral soln: do not take with
cola or tea; M-tab: dissolve on tongue with or without fluid; Consta: administer
deep IM in the deltoid or gluteal; give with oral rispirodone or other antipsychotic
x 3 weeks; then stop oral form; 25 mg IM every 2 weeks; max 50 mg every 2
weeks
Risperdal
Pediatric: <5 years: not established; 5-10 years: initially 0.5 mg once daily at the
same time each day adjust at 24 hour intervals by 0.5-1 mg to target dose 1-2.5
mg/day; usual range 1-6 mg/day; max 6 mg/day; >10 years: same as adult
Tab: 0.25, 0.5, 1, 2, 3, 4 mg; Oral soln: 1 mg/ml (100 ml)
Risperdal Consta
Pediatric: <18 years: not established
Vial: 12.5, 25, 37.5, 50 mg pwdr for long-acting IM inj after reconstitution,
single-use, w. diluent and supplies
Risperdal M-Tab
Pediatric: <10 years: not established; =10 years: same as adult
Tab: 0.5, 1, 2, 3, 4 mg orally-disint (phenylalanine)
Comment: Risperdol tabs, oral solution, and M-tabs are indicated for the shortterm
monotherapy of acute mania or mixed episodes associated with bipolar
I disorder, or in combination with lithium or valproic acid in adults Risperdol
Consta is indicated as monotherapy or adjunctive therapy to lithium or valproic
acid for the maintenance treatment mania and mixed episodes in bipolar I
disorder.
ziprasidone (C)(G) Adult: take with food; initially 40 mg bid; on day 2, may increase
to 60-80 mg bid; Elderly: lower initial dose and titrate slowly
Pediatric: not recommended
Geodon Cap: 20, 40, 60, 80 mg
Comment: Geodon is indicated for acute and maintenance treatment of mania
and mixed episodes in bipolar I disorder, as monotherapy or as adjunct to
lithium or valproic acid.
BITE: CAT
TETANUS PROPHYLAXIS
tetanus toxoid vaccine (C) 0.5 ml IM x 1 dose if previously immunized
Vial: 5 Lf units/0.5 ml (0.5, 5 ml); Prefilled syringe: 5 Lf units/0.5 ml (0.5 ml)
see Tetanus page 408 for patients not previously immunized
ANTI-INFECTIVES
amoxicillin/clavulanate (B)(G) 500 mg tid or 875 mg bid x 10 days
Augmentin Tab: 250, 500, 875 mg; Chew tab: 125, 250 mg (lemon-lime); 200,
400 mg (cherry-banana) (phenylalanine); Oral susp: 125 mg/5 ml (banana), 250
mg/5 ml (75, 100, 150 ml) (orange); 200, 400 mg/5 ml (50, 75, 100 ml) (orange)
(phenylalanine)
Pediatric: 40-45 mg/kg/day divided tid x 10 days or 90 mg/kg/day divided
bid x 10 days see page 556 for dose by weight
Augmentin ES-600 Oral susp: 600 mg/5 ml (50, 75, 100, 125, 150, 200 ml)
(strawberry cream) (phenylalanine) every 12 hours
Pediatric: <3 months: not recommended; =3 months, <40 kg: 90 mg/kg/day
in 2 divided doses; =40 kg: not recommended
Augmentin XR 2 tabs q 12 hours x 7-10 days
Pediatric: <16 years: use other forms; =16 years: same as adult
Tab: 1000*mg ext-rel
cefuroxime axetil (B)(G) 500 mg bid x 10 days
Pediatric: 15 mg/kg bid x 10 days; see page 567 for dose by weight
Ceftin Tab: 250, 500 mg; Oral susp: 125, 250 mg/5 ml (50, 100 ml) (tutti-frutti)
doxycycline (D)(G) 100 mg bid day 1; then 100 mg daily x 10 days
Pediatric: <8 years: not recommended =8 years, <100 lb: 2 mg/lb on first day in
2 divided doses, followed by 1 mg/lb/day in 1-2 divided doses; =8 years, =100 lb:
same as adult; see page 572 for dose by weight
Actilate Tab: 75, 150**mg
Adoxa Tab: 50, 75, 100, 150 mg ent-coat
Doryx Tab: 50, 75, 100, 150, 200 mg del-rel
Monodox Cap: 50, 75, 100 mg
Oracea Cap: 40 mg del-rel
Vibramycin Tab: 100 mg; Cap: 50, 100 mg; Syr: 50 mg/5 ml (raspberry-apple)
(sulfites); Oral susp: 25 mg/5 ml (raspberry)
Vibra-Tab Tab: 100 mg fi lm-coat
Comment: doxycycline is contraindicated <8 years-of-age, in pregnancy, and
lactation (discolors developing tooth enamel). A side effect may be photo-sensitivity
(photophobia). Do not give with antacids, calcium supplements, milk or other dairy,
or within two hours of taking another drug.
penicillin V potassium (B)(G) 500 mg PO qid x 3 days
Pediatric: 15-50 mg/kg/day in 3-6 divided doses x 3 days; =12 years: same as adult;
see page 583 for dose by weight
Pen-Vee K Tab: 250, 500 mg; Oral soln: 125 mg/5 ml (100, 200 ml); 250 mg/5 ml
(100, 150, 200 ml)
BITE: DOG
TETANUS PROPHYLAXIS
tetanus toxoid vaccine (C) 0.5 ml IM x 1 dose if previously immunized
Vial: 5 Lf units/0.5 ml (0.5, 5 ml); Prefilled syringe: 5 Lf units/0.5 ml (0.5 ml)
see Tetanus page 408 for patients not previously immunized
ANTI-INFECTIVES
amoxicillin/clavulanate (B)(G) 500 mg tid or 875 mg bid x 10 days
Augmentin Tab: 250, 500, 875 mg; Chew tab: 125, 250 mg (lemon-lime); 200,
400 mg (cherry-banana) (phenylalanine); Oral susp: 125 mg/5 ml (banana), 250
mg/5 ml (75, 100, 150 ml) (orange); 200, 400 mg/5 ml (50, 75, 100 ml) (orange)
(phenylalanine)
Pediatric: 40-45 mg/kg/day divided tid x 10 days or 90 mg/kg/day divided
bid x 10 days see page 556 for dose by weight
Augmentin ES-600 Oral susp: 600 mg/5 ml (50, 75, 100, 125, 150, 200 ml)
(strawberry cream) (phenylalanine) every 12 hours
Pediatric: <3 months: not recommended; =3 months, <40 kg: 90 mg/kg/day
in 2 divided doses; =40 kg: not recommended
Augmentin XR 2 tabs q 12 hours x 7-10 days
Pediatric: <16 years: use other forms; =16 years: same as adult
Tab: 1000*mg ext-rel
clindamycin (B) (administer with fluoroquinolone in adult and TMP-SMX in children)
300 mg qid x 10 days
Pediatric: 8-16 mg/kg/day in 3-4 divided doses x 10 days; see page 570 for dose by
weight
Cleocin (G) Cap: 75 (tartrazine), 150 (tartrazine), 300 mg
Cleocin Pediatric Granules (G) Oral susp: 75 mg/5 ml (100 ml)(cherry)
doxycycline (D)(G) 100 mg bid
Pediatric: <8 years: not recommended =8 years, <100 lb: 2 mg/lb on first day in 2
divided doses, followed by 1 mg/lb/day in 1-2 divided doses; =8 years, =100 lb: same
as adult; see page 572 for dose by weight
Actilate Tab: 75, 150**mg
Adoxa Tab: 50, 75, 100, 150 mg ent-coat
Doryx Tab: 50, 75, 100, 150, 200 mg del-rel
Monodox Cap: 50, 75, 100 mg
Oracea Cap: 40 mg del-rel
Vibramycin Tab: 100 mg; Cap: 50, 100 mg; Syr: 50 mg/5 ml (raspberry-apple)
(sulfites); Oral susp: 25 mg/5 ml (raspberry)
Vibra-Tab Tab: 100 mg fi lm-coat
Comment: doxycycline is contraindicated <8 years-of-age, in pregnancy, and
lactation (discolors developing tooth enamel). A side effect may be photosensitivity
(photophobia). Do not give with antacids, calcium supplements, milk or
other dairy, or within two hours of taking another drug.
penicillin V potassium (B)(G) 500 mg PO qid x 3 days
Pediatric: 50 mg/kg/day in 4 divided doses x 3 days; =12 years: same as adult; see
page 583 for dose by weight
Pen-Vee K Tab: 250, 500 mg; Oral soln: 125 mg/5 ml (100, 200 ml); 250 mg/5 ml
(100, 150, 200 ml)
BITE: HUMAN
TETANUS PROPHYLAXIS
tetanus toxoid vaccine (C) 0.5 ml IM x 1 dose if previously immunized
Vial: 5 Lf units/0.5 ml (0.5, 5 ml)
Prefilled syringe: 5 Lf units/0.5 ml (0.5 ml)
see Tetanus page 408 for patients not previously immunized
ANTI-INFECTIVES
amoxicillin/clavulanate (B)(G) 500 mg tid or 875 mg bid x 10 days
Augmentin Tab: 250, 500, 875 mg; Chew tab: 125, 250 mg (lemon-lime); 200,
400 mg (cherry-banana) (phenylalanine); Oral susp: 125 mg/5 ml (banana), 250
mg/5 ml (75, 100, 150 ml) (orange); 200, 400 mg/5 ml (50, 75, 100 ml) (orange)
(phenylalanine)
Pediatric: 40-45 mg/kg/day divided tid x 10 days or 90 mg/kg/day divided
bid x 10 days see page 556 for dose by weight
Augmentin ES-600 Oral susp: 600 mg/5 ml (50, 75, 100, 125, 150, 200 ml)
(strawberry cream) (phenylalanine) every 12 hours
Pediatric: <3 months: not recommended; =3 months, <40 kg: 90 mg/kg/day
in 2 divided doses; =40 kg: not recommended y
Augmentin XR 2 tabs q 12 hours x 7-10 days
Pediatric: <16 years: use other forms; =16 years: same as adult
Tab: 1000*mg ext-rel
cefoxitin (B) 80-160 mg/kg/day IM in 3-4 divided doses x 10 days; max 12 g/day
Pediatric: <3 months: not recommended; =3 months: same as adult
Mefoxin Injectable Vial: 1, 2 g
ciprofloxacin (C) 500 mg bid x 10 days
Pediatric: <18 years: not recommended
Cipro (G) Tab: 250, 500, 750 mg; Oral susp: 250, 500 mg/5 ml (100 ml)
(strawberry)
Cipro XR Tab: 500, 1000 mg ext-rel
ProQuin XR Tab: 500 mg ext-rel
Comment: ciprofloxacin is contraindicated <18 years-of-age, and during pregnancy
and lactation. Risk of tendonitis or tendon rupture, especially 60 years-of-age and older.
erythromycin base (B)(G) 250 mg qid x 10 days
Pediatric: <45 kg: 30-40 mg/kg/day in 4 divided doses x 10 days; =45 kg: same as adult
Ery-Tab Tab: 250, 333, 500 mg ent-coat
PCE Tab: 333, 500 mg
Comment: erythromycin may increase INR with concomitant warfarin, as well as
increase serum level of digoxin, benzodiazepines and statins.
erythromycin ethylsuccinate (B)(G) 400 mg qid x 10 days
Pediatric: 30-50 mg/kg/day in 4 divided doses x 10 days; may double dose with
severe infection; max 100 mg/kg/day; see page 574 for dose by weight
EryPed Oral susp: 200 mg/5 ml (100, 200 ml) (fruit); 400 mg/5 ml (60, 100,
200 ml) (banana); Oral drops: 200, 400 mg/5 ml (50 ml) (fruit); Chew tab:
200 mg wafer (fruit)
E.E.S. Oral susp: 200, 400 mg/5 ml (100 ml) (fruit)
E.E.S. Granules Oral susp: 200 mg/5 ml (100, 200 ml) (cherry)
E.E.S. 400 Tablets Tab: 400 mg
Comment: erythromycin may increase INR with concomitant warfarin, as well as
increase serum level of digoxin, benzodiazepines and statins.
trimethoprim/sulfamethoxazole (D)(G) bid x 10 days
Pediatric: <2 months: not recommended; =2 months: 40 mg/kg/day of sulfamethoxazole
in 2 divided doses bid x 10 days; see page 587 for dose by weight
Bactrim, Septra 2 tabs bid x 10 days
Tab: trim 80 mg/sulfa 400 mg*
Bactrim DS, Septra DS 1 tab bid x 10 days
Tab: trim 160 mg/sulfa 800 mg*
Bactrim Pediatric Suspension, Septra Pediatric Suspension
Oral susp: trim 40 mg/sulfa 200 mg per 5 ml (100 ml) (cherry) (alcohol 0.3%)
Comment: trimethoprim/sulfamethoxazole is not recommended in pregnancy or
lactation. CrCl 15-30 mL/min: reduce dose by 1/2; CrCl <15 mL/min: not recommended
BLEPHARITIS
OPHTHALMIC AGENTS
erythromycin ophthalmic ointment (B) apply 1/2 inch bid-qid x 14 days; then q HS
x 10 days
Pediatric: same as adult
Ilotycin Oint: 5 mg/g (1/2 oz)
polymyxin/bacitracin ophthalmic ointment (C) apply 1/2 inch bid-qid x 14 days;
then q HS
Pediatric: same as adult
Polysporin Oint: poly B 10,000 U/baci 500 U (3.75 g)
polymyxin B/bacitracin/neomycin ophthalmic ointment (C) apply 1/2 inch bid-qid
x 14 days; then q HS
Pediatric: same as adult
Neosporin Oint: poly B 10,000 U/baci 400 U/neo 3.5 mg/g (3.75 g)
sodium sulfacetamide (C)
Bleph-10 Ophthalmic Solution 2 drops q 4 hours x 7-14 days
Pediatric: <2 years: not recommended; =2 years: 1-2 drops q 2-3 hours
during the day x 7-14 days
Ophth soln: 10% (2.5, 5, 15 ml) (benzalkonium chloride)
Bleph-10 Ophthalmic Ointment apply 1/2 inch qid and HS x 7-14 days
Pediatric: <2 years: not recommended; >2 years: same as adult
Ophth oint: 10% (3.5 g) (phenylmercuric acetate)
SYSTEMIC AGENTS
tetracycline (D)(G) 250 mg qid x 7 days
Pediatric: <8 years: not recommended; =8 years, <100 lb: 25-50 mg/kg/day in
2-4 divided doses x 7-10 days; =100 lb: same as adult; see page 585 for dose by
weight
Achromycin V Cap: 250, 500 mg
Sumycin Tab: 250, 500 mg; Cap: 250, 500 mg; Oral susp: 125 mg/5 ml (100,
200 ml) (fruit) (sulfites)
Comment: tetracycline is contraindicated <8 years-of-age, in pregnancy, and
lactation (discolors developing tooth enamel). A side effect may be photosensitivity
(photophobia). Do not give with antacids, calcium supplements, milk or
other dairy, or within two hours of taking another drug.
BREAST CANCER: PROPHYLAXIS
ANTI-ESTROGEN AGENTS
fulvestrant (D) 250 mg IM once monthly; administer 2.5 ml IM in each buttock concurrently
Faslodex Prefilled syringe: 50 mg/ml (2 x 2.5 ml, 1 x 5 ml)
letrozole (D)(G) 2.5 mg daily
Femara Tab: 2.5 mg fi lm-coat
Comment: letrozole is indicated for the extended adjuvant treatment of early breast
cancer in postmenopausal women, who have received 5 years of adjuvant tamoxifen
therapy.
tamoxifen citrate (D)(G) 20 mg once daily x 5 years
Tab: 10, 20 mg
Comment: Cautious use of tamoxifen with concomitant coumarin-type
anticoagulation therapy, history of DVT, or history of pulmonary embolus.
BRONCHIOLITIS
Inhaled Beta2-Agonists (Bronchodilators) see Asthma page 29
Oral Beta2-Agonists (Bronchodilators) see Asthma page 35
Inhaled Corticosteroids see Asthma page 29
Parenteral Corticosteroids see page 511
Oral Corticosteroids see page 509
BRONCHITIS: ACUTE/
ACUTE EXACERBATION OF CHRONIC
BRONCHITIS (AECB)
Comment: Antibiotics are seldom needed for treatment of acute bronchitis because the
etiology is usually viral.
Inhaled Beta2-Agonists (Bronchodilators) see Asthma page 29
Oral Beta2-Agonists (Bronchodilators) see Asthma page 35
Decongestants see page 353
Expectorants see page 353
Antitussives see page 353
ANTI-INFECTIVES FOR SECONDARY BACTERIAL INFECTION
amoxicillin (B)(G) 500-875 mg bid or 250-500 mg tid x 10 days
Pediatric: <40 kg (88 lb): 20-40 mg/kg/day in 3 divided doses x 10 days or 25-45
mg/kg/day in 2 divided doses x 10 days; =40 kg: same as adult; see page 554 for dose
by weight
Amoxil Cap: 250, 500 mg; Tab: 875*mg; Chew tab: 125, 200, 250, 400 mg (cherry-
banana-peppermint) (phenylalanine); Oral susp: 125, 250 mg/5 ml (80, 100,
150 ml) (strawberry); 200, 400 mg/5 ml (50, 75, 100 ml) (bubble gum); Oral
drops: 50 mg/ml (30 ml) (bubble gum)
Moxatag Tab: 775 mg ext-rel
Trimox Tab: 125, 250 mg; Cap: 250, 500 mg; Oral susp: 125, 250 mg/5 ml (80,
100, 150 ml) (raspberry-strawberry)
amoxicillin/clavulanate (B)(G) 500 mg tid or 875 mg bid x 10 days
Augmentin Tab: 250, 500, 875 mg; Chew tab: 125, 250 mg (lemon-lime); 200,
400 mg (cherry-banana) (phenylalanine); Oral susp: 125 mg/5 ml (banana), 250
mg/5 ml (75, 100, 150 ml) (orange); 200, 400 mg/5 ml (50, 75, 100 ml) (orange)
(phenylalanine)
Pediatric: 40-45 mg/kg/day divided tid x 10 days or 90 mg/kg/day divided
bid x 10 days see page 556 for dose by weight
Augmentin ES-600 Oral susp: 600 mg/5 ml (50, 75, 100, 125, 150, 200 ml)
(strawberry cream) (phenylalanine) every 12 hours
Pediatric: <3 months: not recommended; =3 months, <40 kg: 90 mg/kg/day
in 2 divided doses; =40 kg: not recommended
Augmentin XR 2 tabs q 12 hours x 7-10 days
Pediatric: <16 years: use other forms; =16 years: same as adult
Tab: 1000*mg ext-rel
ampicillin (B) 250-500 mg qid x 10 days
Pediatric: not recommended for bronchitis in children
Omnipen, Principen Cap: 250, 500 mg; Oral susp: 125, 250 mg/5 ml (100, 150,
200 ml) (fruit)
azithromycin (B) 500 mg x 1 dose on day 1, then 250 mg daily on days 2-5 or
500 mg once daily x 3 days or 2 g in a single dose
Pediatric: not recommended for bronchitis in children
Zithromax Tab: 250, 500, 600 mg; Oral susp: 100 mg/5 ml (15 ml); 200 mg/5 ml
(15, 22.5, 30 ml) (cherry); Pkt: 1 g for reconstitution (cherry-banana)
Zithromax Tri-pak Tab: 3 x 500 mg tabs/pck
Zithromax Z-pak Tab: 6 x 250 mg tabs/pck
Zmax Oral susp: 2 g ext-rel for reconstitution (cherry-banana) (148 mg Na+)
cefaclor (B)(G) 250-500 mg q 8 hours x 10 days; max 2 g/day
Tab: 500 mg; Cap: 250, 500 mg; Susp: 125 mg/5 ml (75, 150 ml) (strawberry);
187 mg/5 ml (50, 100 ml) (strawberry); 250 mg/5 ml (75, 150 ml) (strawberry);
375 mg/5 ml (50, 100 ml) (strawberry)
Pediatric: <16 years: ext-rel not recommended; =16 years: same as adult
Cefaclor Extended Release Tab: 375, 500 mg ext-rel
cefadroxil (B) 1-2 g in 1-2 divided doses x 10 days
Pediatric: 30 mg/kg/day in 2 divided doses x 10 days; see page 561 for dose by weight
Duricef Tab: 1 g; Cap: 500 mg; Oral susp: 250 mg/5 ml (100 ml); 500 mg/5 ml
(75, 100 ml) (orange-pineapple)
cefdinir (B) 300 mg bid x 5-10 days or 600 mg daily x 10 days
Pediatric: <6 months: not recommended; 6 months-12 years: 14 mg/kg/day in
1-2 divided doses x 10 days; =12 years: same as adult; see page 562 for dose by
weight
Omnicef Cap: 300 mg; Oral susp: 125 mg/5 ml (60, 100 ml) (strawberry)
cefditoren pivoxil (B) 400 mg bid x 10 days
Pediatric: not recommended
Spectracef Tab: 200 mg
Comment: Spectracef is contraindicated with milk protein allergy or carnitine
deficiency.
cefixime (B)(G)
Pediatric: <6 months: not recommended; =6 months-12 years, <50 kg: 8 mg/kg/
day in 1-2 divided doses x 10 days; =12 years, >50 kg: same as adult; see page 563 for
dose by weight
Suprax Tab: 400 mg; Cap: 400 mg; Oral susp: 100, 200 mg/5 ml (50, 75, 100 ml)
(strawberry)
cefpodoxime proxetil (B) 200 mg bid x 10 days
Pediatric: <2 months: not recommended; =2 months-12 years: 10 mg/kg/day (max
400 mg/dose) or 5 mg/kg/day bid (max 200 mg/dose) x 10 days; >12 years: same as
adult; see page 564 for dose by weight
Vantin Tab: 100, 200 mg; Oral susp: 50, 100 mg/5 ml (50, 75, 100 mg) (lemon creme)
cefprozil (B) 500 mg q 12 hours x 10 days
Pediatric: <2 years: not recommended; 2-12 years: 15 mg/kg q 12 hours x 10 days;
>12 years: same as adult; see page 565 for dose by weight
Cefzil Tab: 250, 500 mg; Oral susp: 125, 250 mg/5 ml (50, 75, 100 ml) (bubble
gum) (phenylalanine)
ceftibuten (B) 400 mg daily x 10 days
Pediatric: 9 mg/kg daily x 10 days; max 400 mg/day; see page 566 for dose by weight
Cedax Cap: 400 mg; Oral susp: 90 mg/5 ml (30, 60, 90, 120 ml); 180 mg/5 ml
(30, 60, 120 ml) (cherry)
ceftriaxone (B)(G) 1-2 g IM daily continued 2 days after signs of infection have disappeared;
max 4 g/day
Pediatric: 50 mg/kg IM daily and continued 2 days after clinical stability
Rocephin Vial: 250, 500 mg; 1, 2 g
cefuroxime axetil (B)(G) 250-500 mg bid x 10 days
Pediatric: 15 mg/kg bid x 10 days; =12 years: same as adult; see page 567 for dose by
weight
Ceftin Tab: 250, 500 mg; Oral susp: 125, 250 mg/5 ml (50, 100 ml) (tutti-frutti)
cephalexin (B)(G) 250-500 mg qid or 500 mg bid x 10 days
Pediatric: 25-50 mg/kg/day in 4 divided doses x 10 days; =12 years: same as adult; see
page 568 for dose by weight
Keflex Cap: 250, 333, 500, 750 mg; Oral susp: 125, 250 mg/5 ml (100, 200 ml)
(strawberry)
clarithromycin (C)(G) 500 mg or 500 mg ext-rel once daily x 7 days
Pediatric: <6 months: not recommended; =6 months: 7.5 mg/kg bid x 7 days; =12
years: same as adult; see page 569 for dose by weight
Biaxin Tab: 250, 500 mg
Biaxin Oral Suspension Oral susp: 125, 250 mg/5 ml (50, 100 ml) (fruit-punch)
Biaxin XL Tab: 500 mg ext-rel
dirithromycin (C)(G) 500 mg daily x 7 days
Pediatric: <12 years: not recommended; =12 years: same as adult
Dynabac Tab: 250 mg
doxycycline (D)(G) 100 mg bid x 10 days
Pediatric: <8 years: not recommended; =8 years, <100 lb: 2 mg/lb on first day in
2 divided doses, followed by 1 mg/lb/day in 1-2 divided doses; =8 years, =100 lb:
same as adult; see page 572 for dose by weight
Actilate Tab: 75, 150**mg
Adoxa Tab: 50, 75, 100, 150 mg ent-coat
Doryx Tab: 50, 75, 100, 150, 200 mg del-rel
Monodox Cap: 50, 75, 100 mg
Oracea Cap: 40 mg del-rel
Vibramycin Tab: 100 mg; Cap: 50, 100 mg; Syr: 50 mg/5 ml (raspberry-apple)
(sulfites); Oral susp: 25 mg/5 ml (raspberry)
Vibra-Tab Tab: 100 mg fi lm-coat
Comment: doxycycline is contraindicated <8 years-of-age, in pregnancy, and
lactation (discolors developing tooth enamel). A side effect may be photosensitivity
(photophobia). Do not give with antacids, calcium supplements, milk
or other dairy, or within two hours of taking another drug.
erythromycin ethylsuccinate (B)(G) 400 mg qid x 7 days
Pediatric: 30-50 mg/kg/day in 4 divided doses x 7 days; may double dose with
severe infection; max 100 mg/kg/day; see page 574 for dose by weight
EryPed Oral susp: 200 mg/5 ml (100, 200 ml) (fruit); 400 mg/5 ml (60, 100,
200 ml) (banana); Oral drops: 200, 400 mg/5 ml (50 ml) (fruit); Chew tab:
200 mg wafer (fruit)
E.E.S. Oral susp: 200, 400 mg/5 ml (100 ml) (fruit)
E.E.S. Granules Oral susp: 200 mg/5 ml (100, 200 ml) (cherry)
E.E.S. 400 Tablets Tab: 400 mg
Comment: erythromycin may increase INR with concomitant warfarin, as well as
increase serum level of digoxin, benzodiazepines and statins.
gemifloxacin (C) 320 mg daily x 5 days
Pediatric: <18 years: not recommended
Factive Tab: 320*mg
Comment: gemifloxacin is contraindicated <18 years-of-age, and during pregnancy
and lactation. Risk of tendonitis or tendon rupture, especially 60 years-of-age and older.
levofloxacin (C) Uncomplicated: 500 mg daily x 7 days; Complicated: 750 mg daily
x 7 days
Pediatric: <18 years: not recommended
Levaquin Tab: 250, 500, 750 mg
Comment: levofloxacin is contraindicated <18 years-of-age, and during pregnancy and
lactation. Risk of tendonitis or tendon rupture, especially 60 years-of-age and older.
loracarbef (B) 200-400 mg bid x 7 days
Pediatric: 30 mg/kg/day in 2 divided doses x 7 days; =12 years: same as adult;
see page 581 for dose by weight
Lorabid Pulvule: 200, 400 mg; Oral susp: 100 mg/5 ml (50, 100 ml);
200 mg/5 ml (50, 75, 100 ml) (strawberry bubble gum)
moxifloxacin (C)(G) 400 mg daily x 5 days
Pediatric: <18 years: not recommended
Avelox Tab: 400 mg; IV soln: 400 mg/250 mg (latex-free, preservative-free)
Comment: moxifloxacin is contraindicated <18 years-of-age and during pregnancy
and lactation. Risk of tendonitis or tendon rupture, especially 60 years-of-age and older.
ofloxacin (C)(G) 400 mg bid x 10 days
Pediatric: <18 years: not recommended
Floxin Tab: 200, 300, 400 mg
Comment: ofloxacin is contraindicated <18 years-of-age and during pregnancy and
lactation. Risk of tendonitis or tendon rupture, especially 60 years-of-age and older.
telithromycin (C) 2 x 400 mg tabs in a singe dose daily x 5 days
Pediatric: <18 years: not recommended
Ketek Tab: 400 mg
tetracycline (D)(G) 250-500 mg qid x 7 days
Pediatric: <8 years: not recommended; =8 years, <100 lb: 25-50 mg/kg/day in 2-4
divided doses x 7 days; =8 years, =100 lb: same as adult; see page 585 for dose by weight
Achromycin V Cap: 250, 500 mg
Sumycin Tab: 250, 500 mg; Cap: 250, 500 mg; Oral susp: 125 mg/5 ml (100,
200 ml) (fruit) (sulfites)
Comment: tetracycline is contraindicated <8 years-of-age, in pregnancy, and
lactation (discolors developing tooth enamel). A side effect may be photosensitivity
(photophobia). Do not give with antacids, calcium supplements, milk
or other dairy, or within two hours of taking another drug.
trimethoprim/sulfamethoxazole (D)(G) bid x 10 days
Pediatric: <2 months: not recommended; =2 months: 40 mg/kg/day of
sulfamethoxazole in 2 divided doses bid x 10 days; =12 years: same as adult;
see page 587 for dose by weight
Bactrim, Septra 2 tabs bid x 10 days
Tab: trim 80 mg/sulfa 400 mg*
Bactrim DS, Septra DS 1 tab bid x 10 days
Tab: trim 160 mg/sulfa 800 mg*
Bactrim Pediatric Suspension, Septra Pediatric Suspension
Oral susp: trim 40 mg/sulfa 200 mg per 5 ml (100 ml) (cherry)
( alcohol 0.3%)
Comment: trimethoprim/sulfamethoxazole is not recommended in pregnancy
or lactation. CrCl 15-30 mL/min: reduce dose by 1/2; CrCl <15 mL/min: not
recommended
BRONCHITIS: CHRONIC/CHRONIC OBSTRUCTIVE
PULMONARY DISEASE (COPD)
Oral Beta2-Agonists (Bronchodilators) see Asthma page 35
Inhaled Corticosteroids see Asthma page 29
Parenteral Corticosteroids see page 511
Oral Corticosteroids see page 509
Inhaled Beta2-Agonists (Bronchodilators) see Asthma page 29
LONG-ACTING INHALED BETA2-AGONIST (LABA)
indacaterol (C) inhale contents of one 75 mcg cap daily
Pediatric: not established
Arcapta Neohaler Neohaler Device/Cap: 75 mcg pwdr for inhalation (5 blister
cards, 6 caps/card)
Comment: Remove cap from blister cap immediately before use. For oral inhalation
with Neohaler device only. indacaterol is indicated for the long-term maintenance
treatment of bronchoconstriction in patients with COPD. Not indicated for treating
asthma, for primary treatment of acute symptoms, or for acute deterioration of COPD.
indacaterol/glycopyrrolate (C) inhale the contents of one cap twice daily
Pediatric: not established
Utibron Neohaler Neohaler Device/Cap: inda 27.5 mcg/glyco 15.6 mcg pwdr for
inhalation (1, 10 blister cards, 6 caps/card)
olodaterol (C)
Pediatric: not established
Striverdi Respimat 12 mcg q 12 hours
Inhal soln: 2.5 mcg/cartridge (metered actuation) (40 g, 60 metered actuations)
(benzalkonium chloride)
salmeterol (C)(G) 1 inhalation q 12 hours
Serevent Diskus
Pediatric: <4 years: not recommended; =4 years: same as adult
Diskus (pwdr): 50 mcg/actuation (60 doses/disk)
INHALED ANTICHOLINERGICS
ipratropium bromide (B)(G)
Pediatric: not recommended
Atrovent 2 inhalations qid; max 12 inhalations/day
Inhaler: 14 g (200 inh)
Atrovent Inhalation Solution 500 mcg by nebulizer tid-qid
Inhal soln: 0.02% (2.5 ml)
Comment: ipatropium bromide is contraindicated with severe hypersensitivity to
milk proteins.
umeclidinium (C) 1 inhalation once daily at the same time each day
Pediatric: not established
Incruse Ellipta Inhal pwdr: 62.5 mcg/inhalation (30 doses) (lactose)
Comment: Incruse Ellipta is contraindicated with allergy to atropine or its
derivatives.
INHALED LONG-ACTING ANTI-CHOLINERGICS (LAA) (ANTIMUSCARINICS)
Comment: Inhaled LAAs are for prophylaxis and chronic treatment, only. Not for
primary (rescue) treatment of acute attack. Avoid getting powder in eyes. Caution
with narrow-angle glaucoma, BPH, bladder neck obstruction, and pregnancy.
Contraindicated with allergy to atropine or its derivatives (e.g., ipratropium). Avoid
other anticholinergic agents.
aclidinium bromide (C) 1 inhalation twice daily using inhaler
Pediatric: not recommended
Tudorza Pressair Inhal device: 400 mcg/actuation (60 doses per inhalation
device)
tiotropium (as bromide monohydrate) (C) 1 inhalation daily using inhaler; do not
swallow caps
Pediatric: not recommended
Spiriva HandiHaler Inhal device: 18 mcg/cap (5, 30, 90 caps w. inhalation device)
ANTI-CHOLINERGIC/INHALED LONG-ACTING BETA2-AGONIST (LABA)
ipratropium/albuterol (C) 1 inhalation qid; max 6 inhalations/day
Pediatric: not established
Combivent Respimat Inhal soln: ipra 20 mcg/alb 100 mcg per inhalation (4 g,
120 inhal)
Comment: Combivent Respimat is contraindicated with atropine allergy.
tiotropium/olodaterol (C) 2 inhalations once daily at the same time each day; max 2
inhalations/day
Pediatric: not established
Stiolto Respimat Inhal soln: tio 2.5 mcg/olo 2.5 mcg per actuation (4 g, 60 inh)
(benzalkonium chloride)
Comment: Stiolto Respimat is not for treating asthma, for relief of acute bronchospasm,
or acutely deteriorating COPD.
umeclidinium/vilanterol (C) 1 inhalation once daily at the same time each day
Pediatric: not established
Anoro Ellipta Inhal soln: ume 62.5 mcg/vila 25 mcg per inhalation (30 doses)
Comment: Anoro Ellipta is contraindicted with severe hypersensitivity to milk
proteins.
CORTICOSTEROID/INHALED LONG-ACTING BETA AGONIST (LABA)
fluticasone furoate/vilanterol (C) 1 inhalation 100/25 once daily at the same time
each day
Pediatric: <17 years: not established
Breo Ellipta 100/25 Inhal pwdr: fl u 100 mcg/vil 25 mcg dry pwdr per inhalation
(30 doses)
Breo Ellipta 200/25 Inhal pwdr: fl u 200 mcg/vil 25 mcg dry pwdr per inhalation
(30 doses)
Comment: Breo Ellipta is contraindicated with severe hypersensitivity to milk
proteins.
METHYLXANTHINES
Comment: Check serum theophylline level just before 5th dose is administered.
Therapeutic theophylline level: 10-20 mcg/ml.
theophylline (C)(G)
Theo-24 initially 300-400 mg once daily at HS; after 3 days, increase to 400-600
mg once daily at HS; max 600 mg/day
Pediatric: <45 kg: initially 12-14 mg/kg/day; max 300 mg/day; increase aft er
3 days to 16 mg/kg/day to max 400 mg; after 3 more days increase to 30 mg/
kg/day to max 600 mg/day; =45 kg: same as adult
Cap: 100, 200, 300, 400 mg ext-rel
Theo-Dur initially 150 mg bid; increase to 200 mg bid after 3 days; then increase
to 300 mg bid after 3 more days
Pediatric: <6 years: not recommended; =6-15 years: initially 12-14 mg/kg/day in
2 divided doses; max 300 mg/day; then increase to 16 mg/kg in 2 divided doses;
max 400 mg/day; then to 20 mg/kg/day in 2 divided doses; max 600 mg/day
Tab: 100, 200, 300 mg ext-rel
Theolair-SR Tab: 200, 250, 300, 500 mg sust-rel
Pediatric: not recommended
Uniphyl 400-600 mg daily with meals
Pediatric: not recommended
Tab: 400*, 600*mg cont-rel
METHYLXANTHINE/EXPECTORANT COMBINATION
dyphylline/guaifenesin (C)
Lufyllin GG 1 tab qid or 15-30 ml qid
Tab: dyphy 200 mg/guaif 200 mg; Elix: dyphy 100 mg/guaif 100 mg per 15 ml
SELECTIVE PHOSPHODIESTERASE 4 (PDE4) INHIBITOR
roflumilast (C)
Pediatric: not recommended
Daliresp 500 mcg once daily
Tab: 500 mcg
Comment: roflumilast is indicated to reduce the risk of COPD exacerbations in
severe COPD patients with chronic bronchitis and a history of exacerbations.
BULIMIA NERVOSA
SELECTIVE SEROTONIN REUPTAKE INHIBITOR (SSRI)
fluoxetine (C)(G)
Prozac initially 20 mg daily; may increase after 1 week; doses >20 mg/day may
be divided into AM and noon doses; usual daily dose 60 mg; max 80 mg/day
Pediatric: <8 years: not recommended; 8-17 years: initially 10-20 mg/day;
start lower weight children at 10 mg/day; if starting at 10 mg daily, may
increase after 1 week to 20 mg daily
Cap: 10, 20, 40 mg; Tab: 30*, 60*mg; Oral soln: 20 mg/5 ml (4 oz) (mint)
Prozac Weekly following daily fluoxetine therapy at 20 mg/day for 13 weeks,
may initiate Prozac Weekly 7 days after the last 20 mg fluoxetine dose
Pediatric: not recommended
Cap: 90 mg ent-coat del-rel pellets
BURN: MINOR
silver sulfadiazine (C)(G) apply topically to burn 1-2 x daily
Pediatric: not recommended
Silvadene Crm: 1% (20, 50, 85, 400, 1000 g jar; 20 g tube)
Comment: silver sulfadiazine is contradicted in sulfa allergy.
TOPICAL/TRANSDERMAL ANESTHETICS
Comment: lidocaine should not be applied to non-intact skin.
lidocaine burn gel (B)(G)
Pediatric: not recommended
lidocaine cream (B)
Pediatric: not recommended
LidaMantle Crm: 3% (1, 2 oz)
Lidoderm Crm: 3% (85 g)
lidocaine lotion (B)
Pediatric: not recommended
LidaMantle Lotn: 3% (177 ml)
lidocaine 5% patch (B)(G) apply up to 3 patches at one time for up to 12 hours/24-
hour period (12 hours on/12 hours off ); patches may be cut into smaller sizes before
removal of the release liner; do not re-use
Pediatric: not recommended
Lidoderm Patch: 5% (10×14 cm; 30/carton)
lidocaine 2.5%/prilocaine 2.5%
Emla Cream (B) (5, 30 g)
BURSITIS
Acetaminophen for IV Infusion see Pain page 306
Oral Prescription NSAIDs see page 501
Other Oral Analgesics see Pain page 308
Topical/Transdermal NSAIDs see Pain page 307
Parenteral Corticosteroids see page 511
Oral Corticosteroids see page 509
Topical Analgesic and Anesthetic Agents see page 499

 

BÀI LIÊN QUAN