ACNE ROSACEA

Comment: All acne rosacea products should be applied sparingly to clean, dry skin as directed. Avoid use of topical corticosteroids.

• ivermectin (C) apply bid
  Soolantra Crm: 1% (30 g)
  Comment: Soolantra is a macrocyclic lactone. Exactly how it works to treat rosacea is unknown.

TOPICAL ALPHA-2 AGONIST

• brimonidine (B) apply once daily
  Pediatric: <18 years: not recommended
  Mirvaso apply to affected area once daily
  Gel: 0.33% (30, 45 g tube; 30 g pump)
  Comment: For persistant erythema; constricts dilated facial blood vessels to reduce redness.

TOPICAL ANTIMICROBIALS

• azelaic acid (B) apply bid
  Azelex Crm: 20% (30, 50 g)
  Finacea Gel: 15% (30 g); Foam: 15% (50 g)
• metronidazole (B) apply to clean dry skin
  MetroCream apply bid
  Emol crm: 0.75% (45 g)
  MetroGel apply once daily
  Gel: 1% (60 g tube; 55 g pump)
  MetroLotion apply bid
  Lotn: 0.75% (2 oz)
• sodium sulfacetamide (C)(G) apply 1-3 x daily
  Klaron Lotn: 10% (2 oz)
• sodium sulfacetamide/sulfur (C)
  Clenia Emollient Cream apply 1-3 x daily
  Wash: sod sulfa 10%/sulfur 5% (10 oz)
  Clenia Foaming Wash wash aff ected area once or twice daily
  Wash: sod sulfa 10%/sulfur 5% (6, 12 oz)
  Rosula Gel apply 1-3 x daily
  Gel: sod sulfa 10%/sulfur 5% (45 ml)
  Rosula Lotion apply tid
  Lotn: sod sulfa 10%/sulfur 5% (45 ml) (alcohol-free)
  Rosula Wash wash bid
  Clnsr: sod sulfa 10%/sulfur 5% (335 ml)

ORAL ANTIMICROBIALS

• doxycycline (D)(G) 40-100 mg bid
  Pediatric: <8 years: not recommended; ≥8 years, <100 lb: 2 mg/lb on fi rst day in 2 divided doses, followed by 1 mg/lb/day in 1-2 divided doses; ≥8 years, ≥100 lb: same as adult; see page 572 for dose by weight
  Actilate Tab: 75, 150** mg
  Adoxa Tab: 50, 75, 100, 150 mg ent-coat
  Doryx Tab: 50, 75, 100, 150, 200 mg del-rel
  Monodox Cap: 50, 75, 100 mg
  Oracea Cap: 40 mg del-rel
  Vibramycin Tab: 100 mg; Cap: 50, 100 mg; Syr: 50 mg/5 ml (raspberry-apple) (sulfites); Oral susp: 25 mg/5 ml (raspberry)
  Vibra-Tab Tab: 100 mg fi lm-coat
  Comment: doxycycline is contraindicated <8 years-of-age, in pregnancy, and lactation (discolors developing tooth enamel). A side eff ect may be photosensitivity (photophobia). Do not give with antacids, calcium supplements, milk or other dairy, or within two hours of taking another drug.
• minocycline (D)(G) 200 mg on fi rst day; then 100 mg q 12 hours x 9 more days
  Pediatric: <8 years: not recommended; ≥8 years, <100 lb: 2 mg/lb on fi rst day in 2 divided doses, followed by 1 mg/lb q 12 hours x 9 more days; ≥8 years, ≥100 lb: same as adult
  Dynacin Cap: 50, 100 mg
  Minocin Cap: 50, 75, 100 mg; Oral susp: 50 mg/5 ml (60 ml) (custard) (sulfites, alcohol 5%)
  Comment: minocycline is contraindicated <8 years-of-age, in pregnancy, and lactation (discolors developing tooth enamel). A side eff ect may be photosensitivity (photophobia). Do not give with antacids, calcium supplements, milk or other dairy, or within two hours of taking another drug.