Actinic Purpura

Sep 16, 2019 admin DA LIỄU 0

Actinic Purpura

Aka: Actinic Purpura, Senile Purpura, Solar Purpura, Bateman Disease

II. Epidemiology

  1. Occurs equally in men and women
  2. Prevalence
    1. Age 60-70 years old: 2%
    2. Age 90-100 years old: 25%

III. History

  1. First described by Bateman in 1818

IV. Pathophysiology

  1. Chronic Sun Exposure resulting in dermal connective tissue damage
  2. Solar Purpura refers to acute Purpura after Sun Exposure, while actinic and Senile Purpura refer to chronic Purpura

V. Risk Factors

  1. Advancing age
  2. Sun Damaged Skin
  3. Aspirin, NSAIDs or Anticoagulant use

VI. Signs

  1. Dark purple patches and Ecchymosis on sun exposed skin
  2. Distribution (common)
    1. Dorsal hands
    2. Extensor Forearms
  3. Timing
    1. Lesions spontaneously resolve within 2 weeks (prolonged to 3 weeks in impaired phagocyte activity)

VII. Management

  1. Sunscreen with UVA and UVB protection
  2. Medications that have been used for Actinic Purpura
    1. Retinol
    2. Alpha hydroxy Acids
    3. Arnica Oil
    4. Ceramides
    5. Niacinamide (Niacin, Vitamin B3)
    6. Phytonadione (Vitamin K1)
  3. Combination product
    1. Moisturizing Bruise Product (DerMend)

VIII. Complications

  1. Post-inflammatory Hyperpigmentation

IX. References

  1. Email communication with Joe Weidner, MD, received 10/3/2018
  2. Ceilley (2017) J Clin Aesthet Dermatol 10(6): 44-50 [PubMed]

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