Total Iron Binding Capacity

Sep 16, 2019 admin HUYẾT HỌC & UNG THƯ 0

Total Iron Binding Capacity

Aka: Total Iron Binding Capacity, TIBC

II. Measurement

  1. Transferrin carries 2 iron atoms per molecule
  2. Transferrin is normally 30% bound to iron
  3. TIBC reflects a measurement of serum Transferrin
    1. Measured by saturating all available binding sites

III. Interpretation: Normal

  1. Range: 250-460 ug/dl

IV. Interpretation: Increased TIBC

  1. Iron Deficiency Anemia
  2. Third trimester Pregnancy
  3. Polycythemia Vera

V. Interpretation: Decreased TIBC

  1. Anemia of Chronic Disease
  2. Hemolytic Anemia
  3. Hemochromatosis
  4. Chronic Liver Disease or Cirrhosis
  5. Hypoproteinemia
  6. Malnutrition
  7. Pernicious Anemia
  8. Sickle Cell Anemia

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