Medication Causes of Edema
Aka: Medication Causes of Edema, Edema Secondary to Medications
II. Mechanism
- Edema is typically due to salt and water retention unless otherwise noted
III. Causes: Antihypertensives
IV. Causes: Endocrine agents
- Corticosteroids
- Estrogen
- Progesterone
- Testosterone
- Insulin
- Thiazolidinedione (e.g. Actos, Avandia)
V. Causes: Neurologic and Psychiatric Medications
- Antidepressants
- Antipsychotics: Phenothiazines
- Thioridazine (Mellaril)
- Chlorpromazine (Thorazine)
- Trifluoperazine (Stelazine)
- Thiothixene (Navane)
- Neurologic Medications
- Dopamine Agonists such as Pramipexole (Mirapex)
- Gabapentin
- Pregabalin
VI. Causes: Chemotherapy
- Interleukin-2 (Increased Vascular permeability)
- Interleukin-4
- Interferon alfa
- Docetaxel (Taxotere)
- Cyclophosphamide
- Cyclosporine
- Mithramycin
- Cytosine Arbinoside
- Granulocyte colony-stmulating factor
- Granulocyte–Macrophage colony stimulating factor
VII. Causes: Miscellaneous agents
VIII. References
- (2019) Presc Lett
- Trayes (2013) Am Fam Physician 88(2): 102-10 [PubMed]